Anthony L Gotter: search on Z-Library

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1

Promotion of Sleep by Suvorexant—A Novel Dual Orexin Receptor Antagonist

Gotter, Anthony L., Winrow, Christopher J., Cox, Christopher D., Doran, Scott M., Tannenbaum, Pamela L., Breslin, Michael J., Garson, Susan L., Fox, Steven V., Harrell, Charles M., Stevens, Joanne

Journal:

Journal of Neurogenetics

Year:

2011

Language:

english

File:

PDF, 416 KB

english, 2011

2

The Discovery of Suvorexant, the First Orexin Receptor Drug for Insomnia

Coleman, Paul J., Gotter, Anthony L., Herring, W. Joseph, Winrow, Christopher J., Renger, John J.

Journal:

Annual Review of Pharmacology

Year:

2017

Language:

english

File:

PDF, 2.40 MB

english, 2017

3

Tricyclic imidazole antagonists of the Neuropeptide S Receptor

B. Wesley Trotter, Kausik K. Nanda, Peter J. Manley, Victor N. Uebele, Cindra L. Condra, Anthony L. Gotter, Karsten Menzel, Martin Henault, Rino Stocco, John J. Renger, George D. Hartman, Mark T. Bilo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1011 KB

english, 2010

4

Synthesis and evaluation of a new series of Neuropeptide S receptor antagonists

Jeffrey Y. Melamed, Amy E. Zartman, Nathan R. Kett, Anthony L. Gotter, Victor N. Uebele, Duane R. Reiss, Cindra L. Condra, Christine Fandozzi, Laura S. Lubbers, Blake A. Rowe, Georgia B. McGaughey, Ma

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 703 KB

english, 2010

5

10.1038/77653

Reppert, Steven M., Gotter, Anthony L., Manganaro, Thomas, Weaver, David R., Kolakowski, Lee F., Possidente, Bernard, Sriram, Sathyanarayanan, MacLaughlin, David T.

Journal:

Nature Neuroscience

Year:

2000

Language:

english

File:

PDF, 419 KB

english, 2000

6

TASK-3 as a potential antidepressant target

Anthony L. Gotter, Vincent P. Santarelli, Scott M. Doran, Pamela L. Tannenbaum, Richard L. Kraus, Thomas W. Rosahl, Hamid Meziane, Marina Montial, Duane R. Reiss, Keith Wessner, Alexander McCampbell,

Journal:

Year:

2011

Language:

english

File:

PDF, 1.38 MB

english, 2011

7

A Major Second Messenger Mediator of Electrophorus electricus Electric Tissue is CaM Kinase II

Anthony L. Gotter, Marcia A. Kaetzel, John R. Dedman

Journal:

Comparative Biochemistry and Physiology Part A: Physiology

Year:

1997

Language:

english

File:

PDF, 752 KB

english, 1997

8

Electrophorus electricus as a Model System for the Study of Membrane Excitability

Anthony L Gotter, Marcia A Kaetzel, John R Dedman

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

1998

Language:

english

File:

PDF, 1.79 MB

english, 1998

9

Mammalian TIMELESS and Tipin are Evolutionarily Conserved Replication Fork-associated Factors

Anthony L. Gotter, Christine Suppa, Beverly S. Emanuel

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.89 MB

english, 2007

10

Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure

Christopher J. Winrow, Keith Q. Tanis, Duane R. Reiss, Alison M. Rigby, Jason M. Uslaner, Victor N. Uebele, Scott M. Doran, Steven V. Fox, Susan L. Garson, Anthony L. Gotter, David M. Levine, Anthony

Journal:

Neuropharmacology

Year:

2010

Language:

english

File:

PDF, 1.07 MB

english, 2010

11

Pharmacological characterization of MK-6096 – A dual orexin receptor antagonist for insomnia

Christopher J. Winrow, Anthony L. Gotter, Christopher D. Cox, Pamela L. Tannenbaum, Susan L. Garson, Scott M. Doran, Michael J. Breslin, John D. Schreier, Steven V. Fox, Charles M. Harrell, Joanne Ste

Journal:

Neuropharmacology

Year:

2012

Language:

english

File:

PDF, 982 KB

english, 2012

12

Tipin, a Novel Timeless-Interacting Protein, is Developmentally Co-expressed with Timeless and Disrupts its Self-association

Anthony L. Gotter

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.22 MB

english, 2003

13

Analysis of human Per4

Anthony L Gotter, Steven M Reppert

Journal:

Molecular Brain Research

Year:

2001

Language:

english

File:

PDF, 1.57 MB

english, 2001

14

Sex-Linked period Genes in the Silkmoth, Antheraea pernyi: Implications for Circadian Clock Regulation and the Evolution of Sex Chromosomes

Anthony L Gotter, Joel D Levine, Steven M Reppert

Journal:

Year:

1999

Language:

english

File:

PDF, 596 KB

english, 1999

15

Cell Physiology Source Book || Electrocytes of Electric Fish

Gotter, Anthony L.

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

16

[Progress in Brain Research] Orexin/Hypocretin System Volume 198 || Orexin receptors as therapeutic drug targets

Gotter, Anthony L.

Year:

2012

Language:

english

File:

PDF, 430 KB

english, 2012

17

The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold

Gotter, Anthony L, Winrow, Christopher J, Brunner, Joseph, Garson, Susan L, Fox, Steven V, Binns, Jacquelyn, Harrell, Charles M, Cui, Donghui, Yee, Ka, Stiteler, Mark, Stevens, Joanne, Savitz, Alan, T

Journal:

BMC Neuroscience

Year:

2013

Language:

english

File:

PDF, 790 KB

english, 2013

18

Discovery of dual orexin receptor antagonists with rat sleep efficacy enabled by expansion of the acetonitrile-assisted/diphosgene-mediated 2,4-dichloropyrimidine synthesis

Roecker, Anthony J., Mercer, Swati P., Harrell, C. Meacham, Garson, Susan L., Fox, Steven V., Gotter, Anthony L., Prueksaritanont, Thomayant, Cabalu, Tamara D., Cui, Donghui, Lemaire, Wei, Winrow, Chr

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 3.77 MB

english, 2014

19

Selective orexin 2 receptor antagonism blocks cue-induced reinstatement, but not nicotine self-administration or nicotine-induced reinstatement

Uslaner, Jason M., Winrow, Christopher J., Gotter, Anthony L., Roecker, Anthony J., Coleman, Paul J., Hutson, Pete H., Le, Anh D., Renger, John J.

Journal:

Behavioural Brain Research

Year:

2014

Language:

english

File:

PDF, 560 KB

english, 2014

20

Pharmacological Validation of Candidate Causal Sleep Genes Identified in an N2 Cross

Brunner, Joseph I., Gotter, Anthony L., Millstein, Joshua, Garson, Susan, Binns, Jacquelyn, Fox, Steven V., Savitz, Alan T., Yang, He S., Fitzpatrick, Karrie, Zhou, Lili, Owens, Joseph R., Webber, And

Journal:

Journal of Neurogenetics

Year:

2011

Language:

english

File:

PDF, 637 KB

english, 2011

21

Cover Picture: Discovery of 5′′-Chloro- N -[(5,6-dimethoxypyridin-2-yl)methyl]-2,2′:5′,3′′-terpyridine-3′-carboxamide (MK-1064): A Selective Orexin 2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia (ChemMedChem 2/2014)

Roecker, Anthony J., Mercer, Swati P., Schreier, John D., Cox, Christopher D., Fraley, Mark E., Steen, Justin T., Lemaire, Wei, Bruno, Joseph G., Harrell, C. Meacham, Garson, Susan L., Gotter, Anthony

Journal:

Year:

2014

Language:

english

File:

PDF, 881 KB

english, 2014

22

Discovery of 5′′-Chloro- N -[(5,6-dimethoxypyridin-2-yl)methyl]-2,2′:5′,3′′-terpyridine-3′-carboxamide (MK-1064): A Selective Orexin 2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia

Roecker, Anthony J., Mercer, Swati P., Schreier, John D., Cox, Christopher D., Fraley, Mark E., Steen, Justin T., Lemaire, Wei, Bruno, Joseph G., Harrell, C. Meacham, Garson, Susan L., Gotter, Anthony

Journal:

Year:

2014

Language:

english

File:

PDF, 737 KB

english, 2014

23

Discovery of piperidine ethers as selective orexin receptor antagonists (SORAs) inspired by filorexant

Raheem, Izzat T., Breslin, Michael J., Bruno, Joseph, Cabalu, Tamara D., Cooke, Andrew, Cox, Christopher D., Cui, Donghui, Garson, Susan, Gotter, Anthony L., Fox, Steven V., Harrell, C. Meacham, Kuduk

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 732 KB

english, 2015

24

Discovery of diazepane amide DORAs and 2-SORAs enabled by exploration of isosteric quinazoline replacements

Roecker, Anthony J., Mercer, Swati P., Bergman, Jeffrey M., Gilbert, Kevin F., Kuduk, Scott D., Harrell, C. Meacham, Garson, Susan L., Fox, Steven V., Gotter, Anthony L., Tannenbaum, Pamela L., Prueks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 653 KB

english, 2015

25

Constructing a Feedback Loop with Circadian Clock Molecules from the Silkmoth, Antheraea pernyi

Chang, Dennis C., McWatters, Harriet G., Williams, Julie A., Gotter, Anthony L., Levine, Joel D., Reppert, Steven M.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 913 KB

english, 2003

26

Cell Physiology Source Book || Electrocytes of Electric Fish

Gotter, Anthony L.

Year:

2001

Language:

english

File:

PDF, 4.53 MB

english, 2001

27

Differential sleep-promoting effects of dual orexin receptor antagonists and GABAAreceptor modulators

Gotter, Anthony L, Garson, Susan L, Stevens, Joanne, Munden, Regina L, Fox, Steven V, Tannenbaum, Pamela L, Yao, Lihang, Kuduk, Scott D, McDonald, Terrence, Uslaner, Jason M, Tye, Spencer J, Coleman,

Journal:

BMC Neuroscience

Year:

2014

Language:

english

File:

PDF, 1.61 MB

english, 2014

28

A Timeless debate: resolving TIM??s noncircadian roles with possible clock function

Gotter, Anthony L.

Journal:

Year:

2006

Language:

english

File:

PDF, 151 KB

english, 2006

29

Quantitative Electroencephalography Within Sleep/Wake States Differentiates GABAA Modulators Eszopiclone and Zolpidem From Dual Orexin Receptor Antagonists in Rats

Fox, Steven V, Gotter, Anthony L, Tye, Spencer J, Garson, Susan L, Savitz, Alan T, Uslaner, Jason M, Brunner, Joseph I, Tannenbaum, Pamela L, McDonald, Terrence P, Hodgson, Robert, Yao, Lihang, Bowlby

Journal:

Neuropsychopharmacology

Year:

2013

Language:

english

File:

PDF, 492 KB

english, 2013

30

Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors

Yin, Jie, Babaoglu, Kerim, Brautigam, Chad A, Clark, Lindsay, Shao, Zhenhua, Scheuermann, Thomas H, Harrell, Charles M, Gotter, Anthony L, Roecker, Anthony J, Winrow, Christopher J, Renger, John J, Co

Journal:

Nature Structural and Molecular Biology

Year:

2016

Language:

english

File:

PDF, 2.09 MB

english, 2016

31

Pharmacological evaluation of orexin receptor antagonists in preclinical animal models of pain

McDonald, Terrence, Liang, Hongyu A., Sanoja, Raul, Gotter, Anthony L., Kuduk, Scott D., Coleman, Paul J., Smith, Karen M., Winrow, Christopher J., Renger, John J.

Journal:

Journal of Neurogenetics

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

32

Orexin 2 Receptor Antagonism is Sufficient to Promote NREM and REM Sleep from Mouse to Man

Gotter, Anthony L., Forman, Mark S., Harrell, Charles M., Stevens, Joanne, Svetnik, Vladimir, Yee, Ka Lai, Li, Xiaodong, Roecker, Anthony J., Fox, Steven V., Tannenbaum, Pamela L., Garson, Susan L., L

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.32 MB

english, 2016

33

Discovery of highly potent and selective orexin 1 receptor antagonists (1-SORAs) suitable for in vivo interrogation of orexin 1 receptor pharmacology

Stump, Craig A., Cooke, Andrew J., Bruno, Joseph, Cabalu, Tamara D., Gotter, Anthony L., Harell, C. Meacham, Kuduk, Scott D., McDonald, Terrence P., O’Brien, Julie, Renger, John J., Williams, Peter D.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 3.64 MB

english, 2016

34

Orexin 2 receptor regulation of the hypothalamic–pituitary–adrenal (HPA) response to acute and repeated stress

Grafe, Laura A., Eacret, Darrell, Luz, Sandra, Gotter, Anthony L., Renger, John J., Winrow, Chris J., Bhatnagar, Seema

Journal:

Year:

2017

Language:

english

File:

PDF, 34.20 MB

english, 2017

35

The dual orexin receptor antagonist, DORA-22, lowers histamine levels in the lateral hypothalamus and prefrontal cortex without lowering hippocampal acetylcholine

Yao, Lihang Leon, Ramirez, Andres, Roecker, Anthony J., Fox, Steven, Uslaner, Jason, Smith, Sean M., Hodgson, Robert, Coleman, Paul J., Renger, John J., Winrow, Christopher J., Gotter, Anthony L.

Journal:

Journal of Neurochemistry

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

36

Altered Sleep and Affect in the Neurotensin Receptor 1 Knockout Mouse

Fitzpatrick, Karrie, Winrow, Christopher J., Gotter, Anthony L., Millstein, Joshua, Arbuzova, Janna, Brunner, Joseph, Kasarskis, Andrew, Vitaterna, Martha H., Renger, John J., Turek, Fred W.

Journal:

Year:

2012

Language:

english

File:

PDF, 893 KB

english, 2012

37

Orexin signaling during social defeat stress influences subsequent social interaction behaviour and recognition memory

Eacret, Darrell, Grafe, Laura A., Dobkin, Jane, Gotter, Anthony L., Rengerb, John J., Winrow, Christopher J., Bhatnagar, Seema

Journal:

Behavioural Brain Research

Year:

2018

Language:

english

File:

PDF, 715 KB

english, 2018

38

Timeless Links Replication Termination to Mitotic Kinase Activation

Dheekollu, Jayaraju, Wiedmer, Andreas, Hayden, James, Speicher, David, Gotter, Anthony L., Yen, Tim, Lieberman, Paul M., Sullivan, Beth A.

Journal:

Year:

2011

Language:

english

File:

PDF, 3.02 MB

english, 2011

39

Orexin receptor antagonist-induced sleep does not impair the ability to wake in response to emotionally salient acoustic stimuli in dogs

Tannenbaum, Pamela L., Stevens, Joanne, Binns, Jacquelyn, Savitz, Alan T., Garson, Susan L., Fox, Steven V., Coleman, Paul, Kuduk, Scott D., Gotter, Anthony L., Marino, Michael, Tye, Spencer J., Uslan

Journal:

Frontiers in Behavioral Neuroscience

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

40

Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators

Ramirez, Andres D., Gotter, Anthony L., Fox, Steven V., Tannenbaum, Pamela L., Yao, Lihang, Tye, Spencer J., McDonald, Terrence, Brunner, Joseph, Garson, Susan L., Reiss, Duane R., Kuduk, Scott D., Co

Journal:

Frontiers in Neuroscience

Year:

2013

Language:

english

File:

PDF, 784 KB

english, 2013

41

Cross-species systems analysis identifies gene networks differentially altered by sleep loss and depression

Scarpa, Joseph R., Jiang, Peng, Gao, Vance D., Fitzpatrick, Karrie, Millstein, Joshua, Olker, Christopher, Gotter, Anthony, Winrow, Christopher J., Renger, John J., Kasarskis, Andrew, Turek, Fred W.,

Journal:

Science Advances

Year:

2018

Language:

english

File:

PDF, 2.77 MB

english, 2018

42

Inhibition of Orexin Signaling Promotes Sleep Yet Preserves Salient Arousability in Monkeys

Tannenbaum, Pamela L., Tye, Spencer J., Stevens, Joanne, Gotter, Anthony L., Fox, Steven V., Savitz, Alan T., Coleman, Paul J., Uslaner, Jason M., Kuduk, Scott D., Hargreaves, Richard, Winrow, Christo

Journal:

Year:

2016

Language:

english

File:

PDF, 762 KB

english, 2016

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